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IGNOU MBC-08 (July 2025 – Dec 2026) Assignment Questions
PART-(A)
1 What are model organisms, and why are they important in biological research? Give characteristics of any two-model organism.
2 (a) Describe how the behaviour of chromosomes at meiosis explains the law of independent assortment.
(b) Describe epistatic and non-epistatic gene interactions.
3 Explain non-mendalian inheritance with suitable examples.
4 (a) Explain how centromere is mapped with respect to a close by gene in Neurospora crassa.
(b) Explain cis- trans test of allelism (complementation test). 5
5 Explain with suitable examples chromosomal and environmental sex determination mechanisms.
PART-(B)
6(a) Explain the significance of studying development biology.
(b)Differentiate between spermatogenesis and oogenesis.
7(a) Write brief note on the characteristics and importance of Hox genes.
(b) What are maternal determinants? Discuss their role in development of Drosophila.
8(a) Discuss the pedigree of an autosomal dominant trait. Name two human diseases with autosomal dominant inheritance.
(b) Explain the Lederberg and Tatum experiment and its inference.
9(a) Describe the human diseases arising due to variation in chromosome number.
(b) Write the Hardy-Weinberg Law and its application.
Write short notes on the following:
i. Piebaldism
ii. Congenital heart diseases
